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Cancer dormancy : ウィキペディア英語版 | Cancer dormancy
Dormancy is a stage in cancer progression where the cells cease dividing but survive in a quiescent state while waiting for appropriate environmental conditions to begin proliferation again.〔Aguirre-Ghiso, Julio A. (2007). Models, mechanisms and clinical evidence for cancer dormancy. Nature. 7, 834 – 846.〕 Quiescence is the state where cells are not dividing but at arrest in the cell cycle in G0-G1.〔 Dormant cancer cells are thought to be present in early tumor progression, in micrometastases, or left behind in minimal residual disease (MRD) after what was thought to be a successful treatment of the primary tumor.〔Paez David, Labonte Melissa J., Bohanes Pierre, Zhang Wu, Benhanim Leonor, Ning Yan, Wakatsuki Takeru, Loupakis Fotios and Lenz Heinz-Josef. (2012). Cancer Dormancy: A Model of Early Dissemination and Late Cancer Recurrence. Clin Cancer Res. 18, 645.〕 ==Mechanism==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Cancer dormancy」の詳細全文を読む
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